A systematic study based on the review of 89 articles related to coronaviruses and drugs taken by patients suffering from previous diseases showed that there is no evidence for or against the use of non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen to treat patients. with COVID-19. However, he noted that other types of drugs, such as TNF blockers and JAK inhibitors, are safe to use, and IL-6 could be beneficial in treating COVID-19.